Precision Medicine in Epilepsy

Cognition in adults with bottom-of-sulcus dysplasia and the consequences of focal resection

CJ Zheng, D Weintrob, M O'Shea, GD Jackson, C Tailby

2026-05-01

Objective: To determine whether there are cognitive consequences of bottom-of-sulcus dysplasia (BOSD) when assessed as adults and ..

Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure

S Ooi, C Tailby, HR Pardoe, PW Carney, M Sethi, J Haderlein, GD Jackson, DN Vaughan

2026-04-01

Objectives: Predicting seizure recurrence following a first unprovoked seizure (FUS) remains a significant clinical challenge, esp..

Epileptogenic lesions in the Australian epilepsy project: A harmonized 3-T magnetic resonance imaging protocol and its diagnostic yield

DN Vaughan, DF Abbott, A Anderson, G Fitt, S Ooi, H Pardoe, D Parker, Y Perchyonok, E Pierre, C Kokkinos, RE Smith, M Stewart, B Tahayori, C Tailby, GD Jackson, Z Ademi, P Kwan, K Oliver, M Pedersen

2026-01-01

Objective: Detection of epilepsy-causing structural brain lesions on magnetic resonance imaging (MRI) is critical for diagnosis, p..

BrainScape: An open-source framework for integrating and preprocessing anatomical MRI datasets

MN Yasinzai, R Mito, M Pedersen

2025-10-22

MRI has revolutionized our ability to investigate and understand brain structure and function in health and disease. A large amoun..

Ten-year projection of adult epilepsy burden in Australia

GM Geethadevi, KJ Jensen, P Kwan, E Foster, G Jackson, Z Chen, Z Ademi, DF Abbott, S Amarasekara, A Anderson, R Hughes, D Hutchison, P Lightfoot, S Mullen, KL Oliver, HR Pardoe, M Pedersen, C Tailby, DN Vaughan, A De Weger

2025-08-01

Objective: The World Health Organization's Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders calls for..

Common pitfalls during model specification in psychophysiological interaction analysis

V He, B Tahayori, DN Vaughan, HR Pardoe, GD Jackson, C Tailby, DF Abbott

2025-01-01

Psychophysiological interaction (PPI) analysis is a widely used regression method in functional neuroimaging for capturing task-de..

Prediction begins with diagnosis: Estimating seizure recurrence risk in the First Seizure Clinic

S Ooi, C Tailby, N Nagino, PW Carney, GD Jackson, DN Vaughan

2024-11-01

Objectives: To assess the feasibility of using a seizure recurrence prediction tool in a First Seizure Clinic, considering (1) the..

Work productivity, quality of life, and care needs: An unfolding epilepsy burden revealed in the Australian Epilepsy Project pilot study

Clara Marquina, Emma Foster, Zhibin Chen, David N Vaughan, David F Abbott, Chris Tailby, Graeme D Jackson, Patrick Kwan, Zanfina Ademi

2024-04-01

Objective: Epilepsy is a common and serious neurological disorder. This cross-sectional analysis addresses the burden of epilepsy ..

Systematic Review of Cost-Effectiveness Analysis for Surgical and Neurostimulation Treatments for Drug-Resistant Epilepsy in Adults

N Ngan Kee, E Foster, C Marquina, A Tan, SST Pang, TJ O'Brien, P Kwan, GD Jackson, Z Chen, Z Ademi

2023-05-02

Background and ObjectivesSurgical and neurostimulator treatments are effective for reducing seizure burden in selected individuals..

The costs of epilepsy in Australia: A productivity-based analysis

E Foster, Z Chen, E Zomer, M Rychkova, P Carney, TJ O'Brien, D Liew, GD Jackson, P Kwan, Z Ademi

2020-12-15

ObjectiveTo determine the health economic burden of epilepsy for Australians of working age by using life table modeling and to mo..

Teleneuropsychology in the time of COVID-19: The experience of The Australian Epilepsy Project

C Tailby, AJ Collins, DN Vaughan, DF Abbott, M O'Shea, C Helmstaedter, GD Jackson

2020-12-01

Purpose: Traditional neuropsychological testing carries elevated COVID-19 risk for both examinee and examiner. Here we describe ho..

Artificial intelligence for clinical decision support in neurology

M Pedersen, K Verspoor, M Jenkinson, M Law, DF Abbott, GD Jackson

2020-01-01

Artificial intelligence is one of the most exciting methodological shifts in our era. It holds the potential to transform healthca..